finddiffer.com › how-do-i-connect-my-dymoHow do I connect my Dymo LabelWriter 450 to my computer? The reasoning behind this is simple: The DYMO Labelwriter 450 doesn’t support 4” x 6” labels. The DYMO Label maximum supported width is 2.2”. For printing 4” x 6” labels, you would need to use the DYMO Label Writer 4XL , as its XL support comes from its ability to print “extra-large” 4-inch wide labels.